Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5552296

CCC1=Cc2ccccc2C1[Zr+2](C1C(CC)=Cc2ccccc21)[SiH](C)C.[Cl-].[Cl-]

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29898383 1.00 CYP11B1 (0.31) CYP11B1CYP11B2
Iodide SCHEMBL29898404 0.97
Fluoride Ion SCHEMBL30986741 0.97
Bromide SCHEMBL29898405 0.97 HTR2A (0.30)
Hydrochloric Acid SCHEMBL29898393 0.88
Hydrochloric Acid SCHEMBL29898381 0.86 CYP11B1 (0.30) CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL29898422 0.85 CYP3A4 (0.31)
Iodide SCHEMBL29898390 0.84
Fluoride Ion SCHEMBL29898385 0.84
Bromide SCHEMBL29898444 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2915824-B1 METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2022-05-25 EP disclosed
EP-2915824-A1 METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS Lummus Novolen Technology Gmbh (DE) 2015-09-09 EP disclosed
EP-2573091-A1 PROCESS FOR RECYCLING OF FREE LIGAND FROM THEIR CORRESPONDING METALLOCENE COMPLEXES Lummus Novolen Technology Gmbh (DE) 2013-03-27 EP disclosed
US-7285608-B2 Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2007-10-23 US disclosed
EP-1740622-A2 METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS Novolen Technology Holdings C.V. (NL) 2007-01-10 EP disclosed
WO-2005105863-A2 METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2005-11-10 WO disclosed
US-20050239979-A1 Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2005-10-27 US disclosed
WO-2000039175-A1 METHOD OF REDUCING TUBE PLUGGING USING PREACTIVATED UNSUPPORTED CATALYSTS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2000-07-06 WO disclosed