Pyrrolidine

Pyrrolidine

SCHEMBL555248

C1CCNC1.CO[SiH2]OC

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
CXCR4 P61073 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrrolidine SCHEMBL28271754 1.00 ALDH1A1 (0.47) ALDH1A1CXCR4SMN1; SMN2
SCHEMBL554962 0.97 ALDH1A1 (0.53) ALDH1A1CXCR4SMN1; SMN2
Piperidine SCHEMBL27906192 0.97 ALDH1A1 (0.53) ALDH1A1CXCR4SMN1; SMN2
Azetidine SCHEMBL28734002 0.94
Aziridine SCHEMBL4113374 0.90 ALDH1A1 (0.41) ALDH1A1CXCR4SMN1; SMN2
Aziridine SCHEMBL28695777 0.90
Piperazine SCHEMBL27893860 0.87 HIF1A (0.43) CXCR4SMN1; SMN2
Azetidine SCHEMBL28957058 0.82
Azepane SCHEMBL28300473 0.76 ALDH1A1 (0.69) ALDH1A1CXCR4SMN1; SMN2
SCHEMBL1975264 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167273-A1 RHEOLOGY MODIFIER AND AMINOSILANE WATERBORNE ADMIXTURE ROHM & HAAS (US) 2023-06-01 US claimed
CN-115443317-A Rheology modifier and aminosilane aqueous mixture 罗门哈斯公司 2022-12-06 CN claimed
US-20250326936-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL INC (US) 2025-10-23 US disclosed
US-12173166-B2 Articles including surface coatings and methods to produce them MAXTERIAL, INC. (US) 2024-12-24 US disclosed
US-20230167273-A1 RHEOLOGY MODIFIER AND AMINOSILANE WATERBORNE ADMIXTURE ROHM & HAAS (US) 2023-06-01 US disclosed
CN-112424269-B Resin composition for foam, and method for producing foam 株式会社钟化 2023-02-28 CN disclosed
CN-115443317-A Rheology modifier and aminosilane aqueous mixture 罗门哈斯公司 2022-12-06 CN disclosed
CN-111526659-B Surface treated copper foil 长春石油化学股份有限公司 2022-05-24 CN disclosed
EP-3816216-A1 RESIN COMPOSITION FOR FOAM, FOAM, AND PRODUCTION METHOD OF FOAM KANEKA CORPORATION (JP) 2021-05-05 EP disclosed
CN-112424269-A Resin composition for foam, and method for producing foam 株式会社钟化 2021-02-26 CN disclosed
EP-3691894-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM Maxterial, Inc. (US) 2020-08-12 EP disclosed
CN-105916891-A Propylene-based polymers with reduced high molecular weight fraction 格雷斯公司 2016-08-31 CN disclosed
CN-105849141-A Propylene ethylene random copolymer suitable for pipe 格雷斯公司 2016-08-10 CN disclosed
US-8889812-B2 Aqueous silane systems based on tris(alkoxysilylalkyl)amines and the use thereof EVONIK DEGUSSA GMBH (DE) 2014-11-18 US disclosed
US-8772432-B2 2014-07-08 US disclosed
US-20140069293-A1 AQUEOUS SILANE SYSTEMS BASED ON TRIS(ALKOXYSILYLALKYL)AMINES AND THE USE THEREOF EVONIK DEGUSSA GMBH (DE) 2014-03-13 US disclosed
US-20130092052-A1 ALKYL- AND AMINO-FUNCTIONALIZED SILOXANES COMPRISING BIS(ALKOXYSILYL)AMINE FOR THE MASS HYDROPHOBIZATION OF INORGANIC BUILDING MATERIALS EVONIK DEGUSSA GMBH (DE) 2013-04-18 US disclosed
US-8298679-B2 Aqueous silane systems based on bis(trialkoxysilylalkyl)amines EVONIK DEGUSSA GMBH (DE) 2012-10-30 US disclosed
US-20120031302-A1 AQUEOUS SILANE SYSTEMS BASED ON TRIS(ALKOXYSILYLALKYL)AMINES AND THE USE THEREOF EVONIK DEGUSSA GMBH (DE) 2012-02-09 US disclosed
US-20110268899-A1 AQUEOUS SILANE SYSTEMS BASED ON BIS(TRIALKOXYSILYLALKYL)AMINES EVONIK DEGUSSA GMBH (DE) 2011-11-03 US disclosed