SCHEMBL5553269

SCHEMBL5553269

CC(C)=[Ti](Oc1cccc(C(C)(C)C)c1)C1=CC=CC1

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
SOD1 P00441 1/20 0.33
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
HTT P42858 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
GRM2 Q14416 1/20 0.32
FFAR1 O14842 2/20 0.31
PPARG P37231 2/20 0.31
PPARD Q03181 2/20 0.31
TRPV1 Q8NER1 1/20 0.31
TRPA1 O75762 1/20 0.30
RAF1 P04049 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL715519 0.99 CYP3A4 (0.33) CYP3A4CYP2C9CYP2C19SOD1LMNA
Hydrochloric Acid SCHEMBL3687058 0.85 SOD1 (0.33) CYP3A4CYP2C9CYP2C19SOD1LMNA
SCHEMBL4410839 0.85 NR4A1 (0.34) CYP3A4CYP2C9CYP2C19SOD1POLB
Hydrochloric Acid SCHEMBL714948 0.84 NR4A1 (0.34) CYP3A4CYP2C9CYP2C19POLBHTT
SCHEMBL5616337 0.84 CYP3A4 (0.35) CYP3A4CYP2C9CYP2C19SOD1LMNA
SCHEMBL4083421 0.83 CA1 (0.32)
SCHEMBL2013003 0.83
Hydrochloric Acid SCHEMBL715131 0.83 CYP3A4 (0.35) CYP3A4CYP2C9CYP2C19SOD1LMNA
Hydrochloric Acid SCHEMBL714526 0.82 CA1 (0.31)
Hydrochloric Acid SCHEMBL715175 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1785429-B1 PROCESS FOR PRODUCING METALLOCENE COMPOUND SUMITOMO CHEMICAL CO (JP) 2012-10-03 EP disclosed
EP-1785429-A1 PROCESS FOR PRODUCING METALLOCENE COMPOUND Sumitomo Chemical Company, Limited (JP) 2007-05-16 EP disclosed