Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 16/20 | 0.60 |
| ▸ | FNTB | P49356 | 15/20 | 0.60 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3499539 | 0.85 | FNTA (0.82) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL3499541 | 0.85 | FNTA (0.82) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL5551933 | 0.76 | FNTA (0.77) | FNTAFNTBPGGT1B | |
| SCHEMBL445627 | 0.75 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL445625 | 0.75 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL31472029 | 0.75 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL3845902 | 0.75 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL5583314 | 0.74 | FNTA (0.72) | FNTAFNTBPGGT1B | |
| SCHEMBL5553376 | 0.73 | FNTA (0.40) | FNTAFNTBPGGT1B | |
| SCHEMBL7855591 | 0.71 | FNTA (1.00) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1744751-A2 | METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2007-01-24 | — | — | EP | claimed |
| WO-2005089502-A2 | METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2005-09-29 | — | — | WO | claimed |