Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5560170 | 0.83 | HTR6 (0.50) | HTR6CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL3426667 | 0.82 | HTR6 (0.65) | HTR6CYP1A2CYP2C9CYP2C19HTT | |
| Hydrochloric Acid SCHEMBL3426369 | 0.82 | HTR6 (0.64) | HTR6CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL3426588 | 0.81 | HTR6 (0.63) | HTR6CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL3429599 | 0.81 | HTR6 (0.65) | HTR6ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3425143 | 0.79 | HTR6 (0.61) | HTR6CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL3426312 | 0.78 | HTR6 (0.59) | HTR6CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL3426573 | 0.73 | HTR6 (0.53) | HTR6CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL4058603 | 0.73 | HTR6 (0.53) | HTR6CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL5785901 | 0.73 | HTR6 (0.53) | HTR6CYP1A2CYP2C9CYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581538-B1 | TETRACYCLIC 3-SUBSTITUTED INDOLES HAVING SEROTONIN RECEPTOR AFFINITY | SUVEN LIFE SCIENCES LTD (IN) | 2007-02-28 | — | — | EP | disclosed |