SCHEMBL5553741

SCHEMBL5553741

Cc1ccc(S(=O)(=O)n2cc(CN3CCN(Cc4ccccc4)CC3)c3ccccc32)c(Br)c1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL946298 0.88 HTR6 (0.74) HTR6
SCHEMBL946857 0.79 HTR6 (0.80) HTR6
SCHEMBL946237 0.79 HTR6 (0.81) HTR6
SCHEMBL946875 0.79 HTR6 (1.00) HTR6
Hydrochloric Acid SCHEMBL947681 0.78 HTR6 (0.79) HTR6
Hydrochloric Acid SCHEMBL946247 0.78 HTR6 (0.98) HTR6
SCHEMBL3595374 0.77 HTR6 (0.69) HTR6
SCHEMBL946439 0.77 HTR6 (0.81) HTR6
SCHEMBL947068 0.75 HTR6 (0.73) HTR6
SCHEMBL946451 0.75 HTR6 (0.66) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1581538-B1 TETRACYCLIC 3-SUBSTITUTED INDOLES HAVING SEROTONIN RECEPTOR AFFINITY SUVEN LIFE SCIENCES LTD (IN) 2007-02-28 EP disclosed