Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 14/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6424039 | 0.94 | PTGS2 (0.49) | CA1CA2PTGS2PTGS1HRH4 | |
| SCHEMBL5553909 | 0.88 | PTGS2 (0.45) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5560111 | 0.84 | PTGS2 (0.66) | CA1CA2PTGS2PTGS1HRH4 | |
| SCHEMBL5554102 | 0.84 | PTGS2 (0.59) | CA1CA2PTGS2PTGS1HRH4 | |
| SCHEMBL5560561 | 0.84 | PTGS2 (0.51) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5560837 | 0.84 | PTGS2 (0.44) | PTGS2PTGS1HRH4 | |
| SCHEMBL5808581 | 0.83 | PTGS2 (0.44) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5558542 | 0.83 | PTGS2 (0.57) | CA1CA2PTGS2PTGS1HRH4 | |
| SCHEMBL5559101 | 0.83 | PTGS2 (0.45) | CA1CA2PTGS2PTGS1HRH4 | |
| SCHEMBL5554091 | 0.83 | PTGS2 (0.57) | CA1CA2PTGS2PTGS1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1643961-A4 | COX-2 AND FAAH INHIBITORS | MICROBIA INC (US) | 2007-09-12 | — | — | EP | disclosed |
| EP-1643961-A2 | COX-2 AND FAAH INHIBITORS | Microbia, Inc. (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005002525-A2 | COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2005-01-13 | — | — | WO | disclosed |