Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5559002 | 0.96 | PTGS2 (0.48) | PTGS2PTGS1CNR1CNR2MEN1 | |
| SCHEMBL6423909 | 0.95 | PTGS2 (0.48) | PTGS2PTGS1CNR1CNR2MEN1 | |
| SCHEMBL6423438 | 0.95 | PTGS2 (0.48) | PTGS2PTGS1CNR1CNR2MEN1 | |
| SCHEMBL6424820 | 0.93 | PTGS2 (0.46) | PTGS2PTGS1CNR1CNR2MEN1 | |
| SCHEMBL6423955 | 0.93 | PTGS2 (0.46) | PTGS2PTGS1CNR1CNR2MEN1 | |
| SCHEMBL6425957 | 0.93 | PTGS2 (0.49) | PTGS2PTGS1CNR1CNR2MEN1 | |
| SCHEMBL6425866 | 0.93 | PTGS2 (0.49) | PTGS2PTGS1CNR1CNR2MEN1 | |
| SCHEMBL6426363 | 0.92 | PTGS2 (0.46) | PTGS2PTGS1CNR1CNR2MEN1 | |
| SCHEMBL6424180 | 0.91 | PTGS2 (0.48) | PTGS2PTGS1CNR1CNR2MEN1 | |
| SCHEMBL6425425 | 0.90 | PTGS2 (0.47) | PTGS2PTGS1CNR1CNR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1643961-A4 | COX-2 AND FAAH INHIBITORS | MICROBIA INC (US) | 2007-09-12 | — | — | EP | disclosed |
| EP-1643961-A2 | COX-2 AND FAAH INHIBITORS | Microbia, Inc. (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005002525-A2 | COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2005-01-13 | — | — | WO | disclosed |