Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426508 | 0.90 | PTGS2 (0.66) | PTGS2PTGS1MAPT | |
| SCHEMBL5559359 | 0.88 | PTGS2 (0.67) | PTGS2PTGS1MAPTAKR1C3AKR1C2 | |
| SCHEMBL5559164 | 0.86 | PTGS2 (0.71) | PTGS2PTGS1MAPTAKR1C3AKR1C2 | |
| SCHEMBL5560630 | 0.86 | PTGS2 (0.67) | PTGS2PTGS1MAPTAKR1C3AKR1C2 | |
| SCHEMBL5554197 | 0.85 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL5559939 | 0.84 | PTGS2 (0.69) | PTGS2PTGS1MAPTAKR1C3AKR1C2 | |
| SCHEMBL5797053 | 0.84 | PTGS2 (0.68) | PTGS2PTGS1MAPTAKR1C3AKR1C2 | |
| SCHEMBL5558185 | 0.84 | PTGS2 (0.70) | PTGS2PTGS1MAPT | |
| SCHEMBL5559957 | 0.84 | PTGS2 (0.66) | PTGS2PTGS1MAPTAKR1C3AKR1C2 | |
| SCHEMBL5559871 | 0.84 | PTGS2 (0.67) | PTGS2PTGS1MAPTAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1643961-A4 | COX-2 AND FAAH INHIBITORS | MICROBIA INC (US) | 2007-09-12 | — | — | EP | disclosed |
| EP-1643961-A2 | COX-2 AND FAAH INHIBITORS | Microbia, Inc. (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005002525-A2 | COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2005-01-13 | — | — | WO | disclosed |