Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5711030 | 1.00 | CA1 (0.40) | CA1CA4 | |
| Acetic Acid SCHEMBL2090071 | 0.84 | FFAR3 (0.39) | — | |
| Bicarbonate SCHEMBL28073937 | 0.84 | CA4 (0.30) | CA4 | |
| Acetic Acid SCHEMBL1528008 | 0.84 | FFAR3 (0.39) | — | |
| Acetic Acid SCHEMBL1566799 | 0.84 | FFAR3 (0.39) | — | |
| Acetic Acid SCHEMBL5711032 | 0.82 | FFAR3 (0.37) | — | |
| Acetic Acid SCHEMBL5554975 | 0.82 | FFAR3 (0.37) | — | |
| Acetic Acid SCHEMBL3991283 | 0.79 | FFAR3 (0.39) | — | |
| Acetic Acid SCHEMBL7531107 | 0.79 | FFAR3 (0.39) | — | |
| Acetic Acid SCHEMBL7210352 | 0.79 | FFAR3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318845-B1 | HYDROPHILIC, LUBRICIOUS MEDICAL DEVICES HAVING CONTRAST FOR MAGNETIC RESONANCE IMAGING | UNION CARBIDE CHEM PLASTIC (US) | 2006-12-20 | — | — | EP | claimed |
| US-6949266-B2 | Hydrophilic, lubricious medical devices having contrast for magnetic resonance imaging | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2005-09-27 | — | — | US | claimed |
| US-20040058082-A1 | Hydrophilic, lubricious medical devices having contrast for magnetic resonance imaging | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION | 2004-03-25 | — | — | US | claimed |
| EP-1318845-A1 | HYDROPHILIC, LUBRICIOUS MEDICAL DEVICES HAVING CONTRAST FOR MAGNETIC RESONANCE IMAGING | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2003-06-18 | — | — | EP | claimed |
| WO-2002022186-A1 | HYDROPHILIC, LUBRICIOUS MEDICAL DEVICES HAVING CONTRAST FOR MAGNETIC RESONANCE IMAGING | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2002-03-21 | — | — | WO | claimed |
| US-7208138-B2 | Contrast enhancement agent for magnetic resonance imaging | DUKE UNIVERSITY (US) | 2007-04-24 | — | — | US | disclosed |
| EP-1318845-B1 | HYDROPHILIC, LUBRICIOUS MEDICAL DEVICES HAVING CONTRAST FOR MAGNETIC RESONANCE IMAGING | UNION CARBIDE CHEM PLASTIC (US) | 2006-12-20 | — | — | EP | disclosed |
| US-20060083689-A1 | Contrast enhancement agent for magnetic resonance imaging | DUKE UNIVERSITY (US) | 2006-04-20 | — | — | US | disclosed |
| US-6972122-B2 | Contrast enhancement agent for magnetic resonance imaging | DUKE UNIVERSITY (US) | 2005-12-06 | — | — | US | disclosed |
| US-6949266-B2 | Hydrophilic, lubricious medical devices having contrast for magnetic resonance imaging | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2005-09-27 | — | — | US | disclosed |
| EP-1379885-A4 | CONTRAST ENHANCEMENT AGENT FOR MAGNETIC RESONANCE IMAGING | UNIV DUKE (US) | 2005-07-06 | — | — | EP | disclosed |
| US-20040058082-A1 | Hydrophilic, lubricious medical devices having contrast for magnetic resonance imaging | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION | 2004-03-25 | — | — | US | disclosed |
| EP-1379885-A2 | CONTRAST ENHANCEMENT AGENT FOR MAGNETIC RESONANCE IMAGING | Duke University (US) | 2004-01-14 | — | — | EP | disclosed |
| EP-1318845-A1 | HYDROPHILIC, LUBRICIOUS MEDICAL DEVICES HAVING CONTRAST FOR MAGNETIC RESONANCE IMAGING | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2003-06-18 | — | — | EP | disclosed |
| US-20020136692-A1 | Contrast enhancement agent for magnetic resonance imaging | DUKE UNIVERSITY | 2002-09-26 | — | — | US | disclosed |
| WO-2002054088-A2 | CONTRAST ENHANCEMENT AGENT FOR MAGNETIC RESONANCE IMAGING | DUKE UNIVERSITY (US) | 2002-07-11 | — | — | WO | disclosed |
| WO-2002022186-A1 | HYDROPHILIC, LUBRICIOUS MEDICAL DEVICES HAVING CONTRAST FOR MAGNETIC RESONANCE IMAGING | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2002-03-21 | — | — | WO | disclosed |