Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | USP2 | O75604 | 2/20 | 0.71 |
| ▸ | HPN | P05981 | 1/20 | 0.71 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.71 |
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.71 |
| ▸ | PDE4A | P27815 | 1/20 | 0.71 |
| ▸ | KDR | P35968 | 1/20 | 0.71 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.71 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthralin SCHEMBL30013383 | 0.84 | MAPT (1.00) | MAPTALDH1A1TDP1MEN1KMT2A | |
| Anthralin SCHEMBL3197 | 0.84 | MAPT (1.00) | MAPTALDH1A1TDP1MEN1KMT2A | |
| Anthralin SCHEMBL29439039 | 0.84 | MAPT (1.00) | MAPTALDH1A1TDP1MEN1KMT2A | |
| Anthralin SCHEMBL7555831 | 0.82 | MAPT (0.96) | MAPTALDH1A1TDP1MEN1KMT2A | |
| Anthralin SCHEMBL188254 | 0.81 | MAPT (0.85) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL11206395 | 0.77 | ALDH1A1 (0.65) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL31509436 | 0.74 | ALDH1A1 (0.71) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL29929084 | 0.74 | ALDH1A1 (0.71) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL1003557 | 0.74 | ALDH1A1 (0.71) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL12775753 | 0.74 | ALDH1A1 (0.71) | MAPTALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1460995-A4 | TRANSDERMAL TRANSPORT OF COMPOUNDS | VITAL HEALTH SCIENCES PTY LTD (AU) | 2007-11-21 | — | — | EP | disclosed |
| EP-1460995-A1 | TRANSDERMAL TRANSPORT OF COMPOUNDS | Vital Health Sciences Pty Ltd. (AU) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003049774-A1 | TRANSDERMAL TRANSPORT OF COMPOUNDS | VITAL HEALTH SCIENCES PTY LTD (AU) | 2003-06-19 | — | — | WO | disclosed |