Sugi Predict

Sugi Predict / Compounds / SCHEMBL5555337

SCHEMBL5555337

SCHEMBL5555337

CCCCCCCCCCC(NC(=O)NC12CC3CC(CC(C3)C1)C2)C(=O)OC(C)CC

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ EPHX2 P34913 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3193990 0.87 EPHX2 (0.58) EPHX2
SCHEMBL5560549 0.86 EPHX2 (0.57) EPHX2
SCHEMBL5559990 0.85 EPHX2 (0.55) EPHX2
SCHEMBL5554998 0.85 EPHX2 (0.57) EPHX2
SCHEMBL5587653 0.85 EPHX2 (0.56) EPHX2
SCHEMBL4298294 0.83 HDAC4 (0.56) EPHX2
SCHEMBL5588396 0.83 EPHX2 (0.54) EPHX2
SCHEMBL3794554 0.82 EPHX2 (0.73) EPHX2
SCHEMBL5559921 0.81 EPHX2 (0.57) EPHX2
SCHEMBL5560678 0.79 EPHX2 (0.63) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1608319-A4 IMPROVED INHIBITORS FOR THE SOLUBLE EPOXIDE HYDROLASE UNIV CALIFORNIA (US) 2007-02-28 — — EP disclosed
WO-2006045119-A9 IMPROVED INHIBITORS FOR THE SOLUBLE EPOXIDE HYDROLASE UNIV CALIFORNIA (US) 2006-05-26 — — WO disclosed
EP-1608319-A2 IMPROVED INHIBITORS FOR THE SOLUBLE EPOXIDE HYDROLASE The Regents of the University of California (US) 2005-12-28 — — EP disclosed
WO-2004089296-A2 IMPROVED INHIBITORS FOR THE SOLUBLE EPOXIDE HYDROLASE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2004-10-21 — — WO disclosed