Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 19/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5560549 | 0.90 | EPHX2 (0.57) | EPHX2 | |
| SCHEMBL5587653 | 0.88 | EPHX2 (0.56) | EPHX2 | |
| SCHEMBL5554998 | 0.88 | EPHX2 (0.57) | EPHX2 | |
| SCHEMBL3193990 | 0.88 | EPHX2 (0.58) | EPHX2 | |
| SCHEMBL5559990 | 0.86 | EPHX2 (0.55) | EPHX2 | |
| SCHEMBL4298294 | 0.84 | HDAC4 (0.56) | EPHX2MEN1KMT2A | |
| SCHEMBL5555337 | 0.83 | EPHX2 (0.56) | EPHX2 | |
| SCHEMBL3794554 | 0.83 | EPHX2 (0.73) | EPHX2 | |
| SCHEMBL27682407 | 0.81 | EPHX2 (0.46) | EPHX2MEN1KMT2A | |
| SCHEMBL5559351 | 0.81 | EPHX2 (0.56) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814875-A2 | IMPROVED INHIBITORS FOR THE SOLUBLE EPOXIDE HYDROLASE | The Regents of the University of California (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006045119-A2 | IMPROVED INHIBITORS FOR THE SOLUBLE EPOXIDE HYDROLASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-04-27 | — | — | WO | disclosed |