Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387024 | 0.86 | HTT (0.50) | HTTSMN1; SMN2KMT2ALMNAMAPT | |
| SCHEMBL5561675 | 0.83 | HTR2B (0.61) | HTTSMN1; SMN2KMT2ALMNAMAPT | |
| SCHEMBL3361515 | 0.77 | HTT (0.50) | HTTSMN1; SMN2KMT2ALMNAMAPT | |
| SCHEMBL1604201 | 0.77 | HTT (0.75) | HTTSMN1; SMN2KMT2ALMNAMEN1 | |
| Hydrochloric Acid SCHEMBL5560095 | 0.73 | CYP1A2 (0.43) | KMT2ALMNAMEN1MAPK1NSD2 | |
| SCHEMBL1604143 | 0.70 | HTR2B (0.69) | HTTSMN1; SMN2KMT2AMEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL1920934 | 0.69 | HTR2B (0.68) | HTTSMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL12710367 | 0.69 | HTT (0.77) | HTTSMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL2419479 | 0.68 | SSTR5 (0.60) | HTTKMT2ALMNAMAPTNPSR1 | |
| SCHEMBL2414937 | 0.66 | SSTR5 (0.58) | HTTKMT2ALMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797099-A1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | Epix Delaware, Inc. (US) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006034511-A1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | EPIX DELAWARE, INC. (US) | 2006-03-30 | — | — | WO | disclosed |