Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 4/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5555388 | 0.86 | HTT (0.48) | HTTSMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL5561675 | 0.80 | HTR2B (0.61) | HTTSMN1; SMN2LMNAMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL5560095 | 0.73 | CYP1A2 (0.43) | LMNAKMT2AMEN1MAPK1NSD2 | |
| SCHEMBL1604780 | 0.71 | HTR2B (0.65) | HTTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL1605139 | 0.67 | HTT (1.00) | HTTSMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL2416949 | 0.66 | SSTR5 (0.50) | HTTSMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL2420375 | 0.65 | SSTR5 (0.51) | HTTLMNAMAPTKMT2AMEN1 | |
| SCHEMBL1604201 | 0.65 | HTT (0.75) | HTTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL3611907 | 0.64 | ACHE (0.61) | HTTLMNAMAPTKMT2ANPSR1 | |
| SCHEMBL2415036 | 0.64 | SSTR5 (0.60) | HTTLMNAMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797099-B1 | PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | EPIX DELAWARE INC (US) | 2010-08-11 | — | — | EP | disclosed |