Adipic Acid

Adipic Acid

SCHEMBL5555748

CNCCO.O=C(O)CCCCC(=O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC18A2SLC6A2SLC6A3

The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.54
FFAR1 O14842 2/20 0.54
FFAR4 Q5NUL3 2/20 0.54
LMNA P02545 2/20 0.52
CAMK2A Q9UQM7 1/20 0.52
TSHR P16473 5/20 0.50
NFKB1 P19838 1/20 0.50
PMP22 Q01453 1/20 0.50
ADRA1A P35348 1/20 0.48
AKR1B1 P15121 1/20 0.48
KDM4A O75164 1/20 0.47
KDM4C Q9H3R0 1/20 0.47
PRMT1 Q99873 1/20 0.46
PPARG P37231 6/20 0.46
PPARD Q03181 6/20 0.46
PPARA Q07869 6/20 0.46
HDAC11 Q96DB2 5/20 0.46
ALDH1A1 P00352 2/20 0.46
TLR2 O60603 2/20 0.46
TDP1 Q9NUW8 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexanoate SCHEMBL1836006 0.92 AKR1B1 (0.64) GPR84FFAR1FFAR4LMNATSHR
Succinic Acid SCHEMBL1833489 0.90 EGLN1 (0.47) GPR84FFAR1FFAR4LMNACAMK2A
Nonanoate SCHEMBL1830988 0.90 GPR84 (0.65) GPR84FFAR1FFAR4LMNATSHR
Heptanoate SCHEMBL1839046 0.90 GPR84 (0.65) GPR84FFAR1FFAR4LMNATSHR
Octanoic Acid SCHEMBL1834276 0.90 GPR84 (0.65) GPR84FFAR1FFAR4LMNATSHR
Sebacic Acid SCHEMBL5550874 0.90 GPR84 (0.65) GPR84FFAR1FFAR4LMNATSHR
Dodecanoate SCHEMBL1835221 0.90 GPR84 (0.65) GPR84FFAR1FFAR4LMNATSHR
Undecanoate SCHEMBL1831730 0.90 GPR84 (0.65) GPR84FFAR1FFAR4LMNATSHR
Undecanoate SCHEMBL5027634 0.90 GPR84 (0.65) GPR84FFAR1FFAR4LMNATSHR
Decanoic Acid SCHEMBL1833738 0.90 GPR84 (0.65) GPR84FFAR1FFAR4LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5472649-A Mixing curable resin and crosslinker suspended in aqueous phase containing surfactant, stabilizer and promoter, warming to reshape and round, separating, drying EASTMAN CHEMICAL COMPANY (US) 1995-12-05 US claimed
WO-1995028434-A1 METHOD FOR PREPARING POWDER COATING COMPOSITIONS HAVING IMPROVED PARTICLE PROPERTIES PPG INDUSTRIES, INC. (US) 1995-10-26 WO claimed
CN-109563681-B Foamable aqueous composition and foamable aqueous composition 伊斯曼柯达公司 2022-10-04 CN disclosed
CN-113166563-B Aqueous composition for the preparation of yarns and fabrics 伊斯曼柯达公司 2022-08-26 CN disclosed
CN-112313292-B Foamed opaque element 伊斯曼柯达公司 2022-06-03 CN disclosed
CN-110582410-B Foamed opaque element with thermally transferred image 伊斯曼柯达公司 2021-12-03 CN disclosed
CN-113166563-A Aqueous composition for the preparation of yarns and fabrics 伊斯曼柯达公司 2021-07-23 CN disclosed
CN-113056511-A Light-blocking article with spacing functional composition 伊斯曼柯达公司 2021-06-29 CN disclosed
CN-112313292-A Light-blocking articles with functional compositions 伊斯曼柯达公司 2021-02-02 CN disclosed
CN-110582410-A foamed opaque element with thermally transferred image 伊斯曼柯达公司 2019-12-17 CN disclosed
US-9120929-B2 Making high density polymer particles EASTMAN KODAK COMPANY (US) 2015-09-01 US disclosed
US-5156905-A Microbeads partially bordered by voids; texture, opacity, low density, sheets, films EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5143765-A Thermoplastic polymer with crosslinked microbeads and slip coated EASTMAN KODAK COMPANY (US) 1992-09-01 US disclosed
US-5141685-A Mixing polyester and crosslinked polymer microbeads, casting film, stretching; forming doughnut shaped voids encircling beads EASTMAN KODAK COMPANY (US) 1992-08-25 US disclosed
US-5100862-A Microvoided supports for receiving element used in thermal dye transfer EASTMAN KODAK COMPANY (US) 1992-03-31 US disclosed
WO-1991017486-A1 RECEIVER SHEET FOR TONER IMAGES EASTMAN KODAK COMPANY (US) 1991-11-14 WO disclosed
EP-0455192-A1 Microvoided supports for receiving element used in thermal dye transfer EASTMAN KODAK COMPANY (US) 1991-11-06 EP disclosed
US-5055371-A Microvoided polymer, nondeforming EASTMAN KODAK COMPANY (US) 1991-10-08 US disclosed
EP-0436178-A2 Shaped articles and photographic element supports made from orientable polymers and polymer microbeads EASTMAN KODAK COMPANY (US) 1991-07-10 EP disclosed
US-4994312-A Polyester or polypropylene with dispersed crosslinked polymer beads coated with slip agent and bordered by void space EASTMAN KODAK COMPANY (US) 1991-02-19 US disclosed