SCHEMBL5555826

SCHEMBL5555826

CCN(CC)c1ccc(C(c2ccc(F)cc2)c2ccc(N(CC)CC)cc2C)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.47
MAPT P10636 4/20 0.42
ALDH1A1 P00352 4/20 0.42
MAPK1 P28482 3/20 0.42
GAA P10253 2/20 0.42
HTT P42858 2/20 0.42
KDM4E B2RXH2 1/20 0.42
THRB P10828 1/20 0.42
GRK6 P43250 1/20 0.41
PKM P14618 1/20 0.41
MCL1 Q07820 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
GFER P55789 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
LMNA P02545 2/20 0.38
ATM Q13315 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
TERT O14746 1/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10952039 0.94 S100B (0.53) S100BMAPTALDH1A1MAPK1GAA
SCHEMBL658351 0.92 S100B (0.51) S100BMAPTALDH1A1MAPK1GAA
SCHEMBL215745 0.89 S100B (0.49) S100BMAPTALDH1A1MAPK1GAA
SCHEMBL29371256 0.89 S100B (0.49) S100BMAPTALDH1A1MAPK1GAA
SCHEMBL656825 0.89 S100B (0.51) S100BMAPTALDH1A1MAPK1GAA
SCHEMBL13804083 0.89 S100B (0.51) S100BMAPTALDH1A1MAPK1GAA
SCHEMBL6248420 0.88 S100B (0.47) S100BMAPTALDH1A1MAPK1GAA
SCHEMBL5555831 0.88 S100B (0.44) S100BMAPTALDH1A1MAPK1GAA
SCHEMBL11105809 0.88 S100B (0.47) S100BMAPTALDH1A1MAPK1GAA
SCHEMBL5556663 0.86 S100B (0.50) S100BMAPTALDH1A1MAPK1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1803034-A2 HOLOGRAPHIC STORAGE MEDIUM General Electric Company (US) 2007-07-04 EP disclosed
WO-2006044243-A2 HOLOGRAPHIC STORAGE MEDIUM GENERAL ELECTRIC COMPANY A CORPORATION OF THE STATE OF NEW YORK (US) 2006-04-27 WO disclosed
US-20060078802-A1 Holographic storage medium SABIC INNOVATIVE PLASTICS IP B.V. 2006-04-13 US disclosed