SCHEMBL5556288

SCHEMBL5556288

CC(C)(C)OC(=O)COc1ccc(C(C)(C)c2ccc(C(C)(c3ccc(OCC(=O)OC(C)(C)C)cc3)c3ccc(OCC(=O)OC(C)(C)C)cc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 3/20 0.51
PSEN2 P49810 3/20 0.51
APH1B Q8WW43 3/20 0.51
NCSTN Q92542 3/20 0.51
APH1A Q96BI3 3/20 0.51
PSENEN Q9NZ42 3/20 0.51
SMN1; SMN2 Q16637 1/20 0.49
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
PTPN1 P18031 1/20 0.44
KDM4E B2RXH2 3/20 0.43
POLB P06746 1/20 0.43
ALDH1A1 P00352 4/20 0.42
HTT P42858 1/20 0.42
GAA P10253 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
PSMB1 P20618 1/20 0.40
PSMB5 P28074 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197953 0.95 SMN1; SMN2 (0.53) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL3822834 0.95 PSEN1 (0.54) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL5274392 0.85 SMN1; SMN2 (0.67) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL21819637 0.83 PSEN1 (0.62) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL14652405 0.82 MAPT (0.53) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL12995868 0.81 SMN1; SMN2 (0.49) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL7194791 0.81 SMN1; SMN2 (0.49) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL5515918 0.80 PSEN1 (0.49) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL17652044 0.80 SMN1; SMN2 (0.64) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL1507666 0.80 SMN1; SMN2 (0.54) SMN1; SMN2MEN1KMT2APOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178639-B2 Polymer for forming organic anti-reflective coating layer DONGJIN SEMICHEM CO., LTD. (KR) 2012-05-15 US disclosed
US-20100266967-A1 POLYMER FOR FORMING ORGANIC ANTI-REFLECTIVE COATING LAYER DONGJIN SEMICHEM CO., LTD (KR) 2010-10-21 US disclosed