Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5533428 | 0.77 | APOBEC3G (0.73) | APOBEC3GALDH1A1TDP1HSD17B10HTR6 | |
| SCHEMBL121410 | 0.77 | APOBEC3G (1.00) | APOBEC3GALDH1A1TDP1HSD17B10HTR6 | |
| SCHEMBL21326159 | 0.73 | APOBEC3G (0.67) | APOBEC3GALDH1A1TDP1HSD17B10HTR6 | |
| SCHEMBL7022399 | 0.73 | APOBEC3G (0.67) | APOBEC3GALDH1A1TDP1HSD17B10HTR6 | |
| SCHEMBL7783984 | 0.73 | APOBEC3G (0.67) | APOBEC3GALDH1A1TDP1HSD17B10HTR6 | |
| SCHEMBL141091 | 0.71 | APOBEC3G (0.64) | APOBEC3GALDH1A1TDP1HSD17B10HTR6 | |
| Ammonia Solution, Strong SCHEMBL28363215 | 0.70 | APOBEC3G (0.61) | APOBEC3GALDH1A1TDP1HSD17B10HTR6 | |
| SCHEMBL28559827 | 0.70 | APOBEC3G (0.61) | APOBEC3GALDH1A1TDP1HSD17B10HTR6 | |
| SCHEMBL13284490 | 0.70 | APOBEC3G (0.75) | APOBEC3GALDH1A1TDP1HSD17B10HTR6 | |
| SCHEMBL26225209 | 0.70 | APOBEC3G (0.75) | APOBEC3GALDH1A1TDP1HSD17B10HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1827446-A2 | SULFONYL SEMICARBAZIDES, SEMICARBAZIDES AND UREAS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR TREATING HEMORRHAGIC FEVER VIRUSES, INCLUDING INFECTIONS ASSOCIATED WITH ARENAVIRUSES | SIGA TECHNOLOGIES, INC. (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006062898-A2 | COMPOUNDS AND METHODS FOR TREATING HEMORRHAGIC FEVER VIRUSES | SIGA TECHNOLOGIES, INC. (US) | 2006-06-15 | — | — | WO | disclosed |