SCHEMBL5556537

SCHEMBL5556537

Cc1cc2c(Br)c3ccccc3c(-c3ccccc3)c2cc1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.40
KDM4E B2RXH2 2/20 0.40
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
TACR1 P25103 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
RPA1 P27694 1/20 0.34
MCL1 Q07820 1/20 0.34
PRNP P04156 1/20 0.34
PPARG P37231 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
NR2E3 Q9Y5X4 1/20 0.34
NCOR2 Q9Y618 1/20 0.34
CYP1A2 P05177 2/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12415320 0.94 ACHE (0.39) ACHEKDM4EMAPTMAPK1TDP1
SCHEMBL27568153 0.88 ACHE (0.48) ACHEKDM4EMAPTMAPK1TDP1
SCHEMBL30396122 0.84 MAPK1 (0.50) ACHEKDM4EMAPTMAPK1TDP1
SCHEMBL295397 0.84 MAPK1 (0.50) ACHEKDM4EMAPTMAPK1TDP1
SCHEMBL30662429 0.84 ACHE (0.46) ACHEMAPTESR1ESR2TACR1
SCHEMBL5556083 0.84 KDM4E (0.42) ACHEKDM4EMAPTL3MBTL1MEN1
SCHEMBL1155242 0.83 ESR1 (0.53) ACHEKDM4EMAPTMAPK1TDP1
SCHEMBL25625149 0.83 MAPK1 (0.41) ACHEKDM4EMAPTMAPK1TDP1
SCHEMBL2185513 0.82 MAPK1 (0.48) ACHEKDM4EMAPTMAPK1TDP1
SCHEMBL12560663 0.82 MAPK1 (0.48) ACHEKDM4EMAPTMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed
US-20050074631-A1 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2005-04-07 US disclosed