Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 14/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 14/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 13/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | GNG2 | P59768 | 1/20 | 0.43 |
| ▸ | GNB1 | P62873 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237712 | 0.85 | FLT1 (0.47) | INSRIGF1RMEN1MMP1MMP9 | |
| SCHEMBL5553477 | 0.75 | CTNNB1 (0.52) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| SCHEMBL5553614 | 0.75 | OPRL1 (0.47) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| SCHEMBL5558098 | 0.74 | SMN1; SMN2 (0.48) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| SCHEMBL5553552 | 0.74 | OPRL1 (0.50) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| SCHEMBL5558062 | 0.73 | CTNNB1 (0.47) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| SCHEMBL5559022 | 0.72 | MMP9 (0.52) | OPRL1MEN1MMP1MMP9ALOX15 | |
| SCHEMBL5559915 | 0.71 | MMP9 (0.49) | MEN1MMP1MMP9ALOX15BLM | |
| SCHEMBL5553523 | 0.71 | NPC1 (0.51) | OPRL1MAPTMEN1MMP1MMP9 | |
| SCHEMBL5558128 | 0.71 | CYP3A4 (0.52) | HDAC6MMP1MMP9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509516-B1 | INHIBITORS OF THE GPIB -VWF INTERACTION, THEIR PREPARATION AND USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-01-31 | — | — | EP | claimed |