Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 10/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5553552 | 0.91 | OPRL1 (0.50) | OPRL1MAPTOPRM1OPRD1OPRK1 | |
| SCHEMBL5553523 | 0.89 | NPC1 (0.51) | OPRL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5553515 | 0.87 | OPRL1 (0.56) | OPRL1MAPTMMP9OPRM1OPRD1 | |
| SCHEMBL3236262 | 0.85 | MMP9 (0.63) | OPRL1MMP9 | |
| SCHEMBL5558248 | 0.84 | PRKCI (0.54) | OPRL1MMP9 | |
| SCHEMBL5558128 | 0.83 | CYP3A4 (0.52) | MMP9HDAC6 | |
| SCHEMBL5559022 | 0.82 | MMP9 (0.52) | OPRL1MMP9 | |
| SCHEMBL5553436 | 0.81 | OPRL1 (0.51) | OPRL1MAPTMMP9 | |
| SCHEMBL5558922 | 0.81 | MMP9 (0.51) | OPRL1MMP9 | |
| SCHEMBL5559915 | 0.79 | MMP9 (0.49) | MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509516-B1 | INHIBITORS OF THE GPIB -VWF INTERACTION, THEIR PREPARATION AND USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-01-31 | — | — | EP | claimed |