Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412758 | 0.88 | MAPT (0.30) | MAPT | |
| SCHEMBL10718713 | 0.82 | MAPT (0.40) | MAPT | |
| SCHEMBL3699545 | 0.75 | — | — | |
| SCHEMBL11593833 | 0.74 | — | — | |
| SCHEMBL1936488 | 0.73 | MAPT (0.39) | MAPT | |
| SCHEMBL11195552 | 0.72 | MAPT (0.45) | MAPT | |
| Chloroform SCHEMBL1937049 | 0.68 | MAPT (0.35) | MAPT | |
| SCHEMBL900953 | 0.65 | MAPT (0.70) | MAPT | |
| SCHEMBL6911275 | 0.65 | MAPT (0.59) | MAPT | |
| SCHEMBL8686787 | 0.64 | KDM1A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220746-B2 | Pyrrolidinedione substituted piperidine-phthalazones as PDE4 inhibitors | ALTANA PHARMA AG (DE) | 2007-05-22 | — | — | US | disclosed |
| EP-1537100-B1 | PYRROLIDINEDIONE SUBSTITUTED PIPERIDINE-PHTHALAZONES AS PDE4 INHIBITORS | ALTANA PHARMA AG (DE) | 2007-04-25 | — | — | EP | disclosed |
| US-20060160813-A1 | Pyrrolidinedione substituted piperidine-phtalazones as pde4 inhibitors | ALTANA PHARMA AG (DE) | 2006-07-20 | — | — | US | disclosed |
| EP-1537100-A1 | PYRROLIDINEDIONE SUBSTITUTED PIPERIDINE-PHTHALAZONES AS PDE4 INHIBITORS | ALTANA Pharma AG (DE) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004018449-A1 | PIPERIDINE-DERIVATIVES AS PDE4 INHIBITORS | ALTANA PHARMA AG (DE) | 2004-03-04 | — | — | WO | disclosed |
| WO-2004018457-A1 | PYRROLIDINEDIONE SUBSTITUTED PIPERIDINE-PHTHALAZONES AS PDE4 INHIBITORS | ALTANA PHARMA AG (DE) | 2004-03-04 | — | — | WO | disclosed |
| EP-1042319-A1 | DIHYDROBENZOFURANS | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999031090-A1 | DIHYDROBENZOFURANS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-06-24 | — | — | WO | disclosed |
| EP-0625978-A1 | PIPERAZINE AND PIPERIDINE DERIVATIVES, AND THEIR USE AS ANTIPSYCHOTICS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-30 | — | — | EP | disclosed |
| EP-0117403-B1 | 6-(ACYLAMINOARYL)-3(2H)-PYRIDAZINONE DERIVATIVES, THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1988-06-01 | — | — | EP | disclosed |
| EP-0117403-A1 | 6-(Acylaminoaryl)-3(2H)-pyridazinone derivatives, their preparation and use | BASF Aktiengesellschaft (DE) | 1984-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160813-A1 | Pyrrolidinedione substituted piperidine-phtalazones as pde4 inhibitors | PDE4A, PDE4B, PDE3B | MAPT 2860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.