Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936488 | 0.93 | MAPT (0.39) | MAPTCCR2MAOAMAOB | |
| SCHEMBL10718713 | 0.77 | MAPT (0.40) | MAPTCCR2MAOAMAOB | |
| SCHEMBL23113739 | 0.69 | MAPT (0.31) | MAPT | |
| SCHEMBL5558586 | 0.68 | MAPT (0.39) | MAPT | |
| SCHEMBL11195552 | 0.67 | MAPT (0.45) | MAPT | |
| SCHEMBL37603 | 0.66 | — | — | |
| SCHEMBL900953 | 0.65 | MAPT (0.70) | MAPTCCR2MAOAMAOB | |
| SCHEMBL6911275 | 0.65 | MAPT (0.59) | MAPTCCR2MAOAMAOB | |
| SCHEMBL2569326 | 0.62 | MAPT (0.51) | MAPTMAOAMAOB | |
| SCHEMBL6244459 | 0.61 | MAPT (0.33) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331540-A1 | BERBERINE COMPOUNDS AND PROCESSES FOR THE PREPARATION OF BERBERINE COMPOUNDS | Mallinckrodt Inc. (US) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010039215-A1 | BERBERINE COMPOUNDS AND PROCESSES FOR THE PREPARATION OF BERBERINE COMPOUNDS | MALLINCKRODT INC. (US) | 2010-04-08 | — | — | WO | disclosed |