Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643966 | 0.87 | MAPT (0.38) | MAPTALDH1A1HPGDTSHRPOLB | |
| Hydrochloric Acid SCHEMBL28884279 | 0.85 | MAPT (0.37) | MAPTALDH1A1HPGDTSHRPOLB | |
| SCHEMBL15313324 | 0.85 | CDK8 (0.37) | MAPTALDH1A1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL27993175 | 0.85 | MAPT (0.37) | MAPTALDH1A1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL9643821 | 0.83 | ALDH1A1 (0.38) | MAPTALDH1A1HPGDTSHRPOLB | |
| SCHEMBL2446926 | 0.83 | MAPT (0.36) | MAPTALDH1A1HPGDTSHRPOLB | |
| SCHEMBL9644338 | 0.82 | MAPT (0.37) | MAPTALDH1A1HPGDTSHRPOLB | |
| SCHEMBL8507216 | 0.81 | ALDH1A1 (0.51) | MAPTALDH1A1HPGDHSP90AA1MEN1 | |
| SCHEMBL10822061 | 0.81 | ALDH1A1 (0.35) | MAPTALDH1A1HPGDPOLBHSP90AA1 | |
| SCHEMBL6137459 | 0.78 | MAPT (0.40) | MAPTALDH1A1HPGDTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104163791-A | N-pyridine (hetero) aryl amide compound and preparation method and application thereof | HUNAN RES INST CHEMICAL IND | 2014-11-26 | — | — | CN | disclosed |
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
| US-5136042-A | PROCESS FOR THE PREPARATION OF THIAZOLECARBOXYLIC ACID CHLORIDES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-08-04 | — | — | US | disclosed |
| EP-0377750-A1 | PROCESS FOR PREPARING THIAZOLECARBOXYLIC ACID CHLORIDES | MITSUI CHEMICALS, INC. (JP) | 1990-07-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | MAPT 2190/4885ALDH1A1 2042/4885HPGD 563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.