Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3114792 | 0.82 | EGFR (0.57) | USP2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL5553089 | 0.77 | EGFR (0.66) | LMNAEGFRPDGFRBKDR | |
| SCHEMBL30366783 | 0.76 | CYP1A2 (0.52) | USP2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL5553119 | 0.73 | EGFR (0.46) | EGFRPDGFRBKDRALDH1A1KDM4E | |
| SCHEMBL5107707 | 0.71 | EGFR (0.67) | USP2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL4894387 | 0.71 | CYP1A2 (0.70) | USP2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL5107758 | 0.71 | CYP1A2 (0.74) | USP2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL4890500 | 0.69 | USP2 (0.55) | USP2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL4884533 | 0.69 | USP2 (0.55) | USP2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL5104641 | 0.69 | CYP1A2 (0.55) | USP2CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833511-A2 | METHOD OF TREATING BRAIN CANCER | MYRIAD GENETICS, INC. (US) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006074187-A2 | METHOD OF TREATING BRAIN CANCER | MYRIAD GENETICS, INC. (US) | 2006-07-13 | — | — | WO | disclosed |