SCHEMBL5560463

SCHEMBL5560463

CCCOC(C=C(C#N)C(=O)O)CC

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.33
SLC16A3 O15427 3/20 0.33
SLC16A1 P53985 3/20 0.33
CISD1 Q9NZ45 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33
GPR35 Q9HC97 1/20 0.33
POLB P06746 1/20 0.32
CYP2C9 P11712 1/20 0.32
LMNA P02545 1/20 0.31
PKM P14618 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5912993 1.00 KDM4E (0.33) KDM4ESLC16A3SLC16A1CISD1ALDH1A1
SCHEMBL1275104 0.91 POLB (0.36) KDM4ESLC16A3SLC16A1CISD1POLB
SCHEMBL1274505 0.87 CYP2C9 (0.37) KDM4ESLC16A3SLC16A1CISD1ALDH1A1
SCHEMBL1275388 0.82 KDM4E (0.33) KDM4ESLC16A3SLC16A1CISD1ALDH1A1
SCHEMBL1275320 0.81 KDM4E (0.36) KDM4ESLC16A3SLC16A1CISD1ALDH1A1
SCHEMBL5555506 0.80 POLB (0.35) KDM4ESLC16A3SLC16A1POLBLMNA
SCHEMBL16814652 0.80 KDM4E (0.34) KDM4ESLC16A3SLC16A1CISD1ALDH1A1
SCHEMBL21932803 0.77 CYP2C9 (0.33) KDM4ESLC16A3SLC16A1CISD1ALDH1A1
SCHEMBL11832041 0.76 HCAR2 (0.32)
SCHEMBL5561889 0.75 KDM4E (0.35) KDM4ESLC16A3SLC16A1CISD1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1360257-B1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS LOCTITE R & D LTD (IE) 2007-07-25 EP claimed