SCHEMBL5561889

SCHEMBL5561889

CCCC(C=C(C#N)C(=O)O)OC

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.35
LMNA P02545 1/20 0.35
PKM P14618 1/20 0.35
KMT2A Q03164 1/20 0.35
SLC16A3 O15427 3/20 0.34
SLC16A1 P53985 3/20 0.34
CISD1 Q9NZ45 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33
GPR35 Q9HC97 1/20 0.33
POLB P06746 1/20 0.33
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1275320 0.86 KDM4E (0.36) KDM4ELMNAPKMKMT2ASLC16A3
SCHEMBL5555506 0.81 POLB (0.35) KDM4ELMNASLC16A3SLC16A1POLB
SCHEMBL1275305 0.77 KDM4E (0.37) KDM4ELMNASLC16A3SLC16A1CISD1
SCHEMBL18606218 0.76 KDM4E (0.35) KDM4ELMNASLC16A3SLC16A1CISD1
SCHEMBL5912993 0.75 KDM4E (0.33) KDM4ELMNAPKMKMT2ASLC16A3
SCHEMBL5560463 0.75 KDM4E (0.33) KDM4ELMNAPKMKMT2ASLC16A3
SCHEMBL7021807 0.75 CHRM1 (0.35) CYP3A4
SCHEMBL16814652 0.75 KDM4E (0.34) KDM4ELMNAPKMKMT2ASLC16A3
SCHEMBL1274505 0.75 CYP2C9 (0.37) KDM4ELMNAPKMKMT2ASLC16A3
SCHEMBL21932827 0.74 KDM4E (0.34) KDM4ELMNAPKMKMT2ASLC16A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1360257-B1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS LOCTITE R & D LTD (IE) 2007-07-25 EP claimed
EP-1317294-B1 ABSORBABLE ADHESIVE COMPOSITIONS CLOSURE MEDICAL CORP (US) 2005-03-16 EP claimed
EP-3329846-B1 COMPOSITION FOR DETECTING LATENT FINGERPRINT TOAGOSEI CO LTD (JP) 2021-07-14 EP disclosed
EP-3327043-B1 CURABLE COMPOSITION TOAGOSEI CO LTD (JP) 2021-04-21 EP disclosed
US-20180368740-A1 COMPOSITION FOR DETECTING LATENT FINGERPRINT TOAGOSEI CO., LTD (JP) 2018-12-27 US disclosed
US-20180208690-A1 CURABLE COMPOSITION TOAGOSEI CO., LTD. (JP) 2018-07-26 US disclosed
EP-3329846-A1 COMPOSITION FOR DETECTING LATENT FINGERPRINT Toagosei Co., Ltd. (JP) 2018-06-06 EP disclosed
EP-3327043-A1 CURABLE COMPOSITION Toagosei Co., Ltd. (JP) 2018-05-30 EP disclosed