Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14454008 | 0.91 | CARM1 (0.33) | MAPTCARM1PRMT6 | |
| SCHEMBL5556070 | 0.86 | SIRT1 (0.34) | MAPTCARM1PRMT6 | |
| SCHEMBL5559204 | 0.85 | CARM1 (0.35) | CARM1PRMT6 | |
| SCHEMBL5556126 | 0.85 | CYP1A2 (0.31) | — | |
| SCHEMBL5555486 | 0.84 | CYP1A2 (0.33) | — | |
| SCHEMBL5556274 | 0.83 | CARM1 (0.39) | MAPTCARM1PRMT6 | |
| SCHEMBL5560997 | 0.83 | CYP1A2 (0.32) | — | |
| SCHEMBL5556006 | 0.82 | PTGDR2 (0.41) | MAPTCARM1PRMT6 | |
| SCHEMBL5557512 | 0.82 | PTGDR2 (0.33) | MAPTCARM1PRMT6 | |
| SCHEMBL14453990 | 0.82 | MAPK8 (0.35) | CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597235-B1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2007-08-15 | — | — | EP | disclosed |
| US-7241794-B2 | Nonnucleoside reverse transcriptase inhibitors | ROCHEPALO ALTO LLC (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241794-B2 | Nonnucleoside reverse transcriptase inhibitors | ROCHEPALO ALTO LLC (US) | 2007-07-10 | — | — | US | disclosed |