Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 11/20 | 0.37 |
| ▸ | GSK3B | P49841 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | WNT1 | P04628 | 5/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176365 | 0.96 | DYRK1A (0.39) | DYRK1AGSK3BMAPTMAPK1ABL1 | |
| Formic Acid SCHEMBL5563354 | 0.92 | DYRK1A (0.35) | DYRK1AGSK3BMAPTMAPK1ABL1 | |
| SCHEMBL1175579 | 0.88 | DYRK1A (0.38) | DYRK1AGSK3BMAPTMAPK1ABL1 | |
| SCHEMBL5044466 | 0.88 | DYRK1A (0.38) | DYRK1AGSK3BMAPTMAPK1ABL1 | |
| Formic Acid SCHEMBL5562107 | 0.84 | GSK3B (0.52) | DYRK1AGSK3BRBP4 | |
| Formic Acid SCHEMBL5562238 | 0.84 | ABL1 (0.37) | GSK3BABL1BCRRBP4HSP90AA1 | |
| Formic Acid SCHEMBL5562495 | 0.83 | CHRNA7 (0.46) | MAPTRBP4 | |
| SCHEMBL1176262 | 0.82 | DYRK1A (0.42) | DYRK1AGSK3BMAPTMAPK1WNT1 | |
| SCHEMBL1176757 | 0.81 | DYRK1A (0.37) | DYRK1AGSK3BMAPTMAPK1WNT1 | |
| SCHEMBL1384710 | 0.81 | CDC7 (0.37) | DYRK1AGSK3BMAPTMAPK1WNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697378-B1 | INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, AND 1,2-BENZISOTHIAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARM CORP (US) | 2007-11-21 | — | — | EP | claimed |