Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 5/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.45 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1175853 | 0.95 | CHRNA7 (0.49) | CHRNA7HTR3ARAB9ANPC1YTHDC1 | |
| Formic Acid SCHEMBL5563473 | 0.91 | YTHDC1 (0.45) | CHRNA7HTR3ARAB9ANPC1YTHDC1 | |
| SCHEMBL1176568 | 0.86 | YTHDC1 (0.49) | CHRNA7HTR3ARAB9ANPC1YTHDC1 | |
| SCHEMBL5038866 | 0.86 | YTHDC1 (0.49) | CHRNA7HTR3ARAB9ANPC1YTHDC1 | |
| Formic Acid SCHEMBL5562469 | 0.83 | DYRK1A (0.37) | RBP4MAPT | |
| Formic Acid SCHEMBL5561747 | 0.83 | GSK3B (0.43) | RBP4FLT3 | |
| Formic Acid SCHEMBL5562107 | 0.83 | GSK3B (0.52) | RBP4 | |
| SCHEMBL2105414 | 0.83 | CHRNA7 (0.46) | CHRNA7HTR3ARAB9ANPC1YTHDC1 | |
| SCHEMBL1176262 | 0.81 | DYRK1A (0.42) | RBP4MAPT | |
| Formic Acid SCHEMBL5562578 | 0.80 | ULK1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697378-B1 | INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, AND 1,2-BENZISOTHIAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARM CORP (US) | 2007-11-21 | — | — | EP | claimed |