Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 19/20 | 0.38 |
| ▸ | GSK3B | P49841 | 10/20 | 0.38 |
| ▸ | WNT1 | P04628 | 5/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 2/20 | 0.35 |
| ▸ | CLK3 | P49761 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1175688 | 0.96 | DYRK1A (0.40) | DYRK1AGSK3BWNT1CHEK1CLK2 | |
| SCHEMBL5043095 | 0.96 | DYRK1A (0.40) | DYRK1AGSK3BWNT1CHEK1CLK2 | |
| Formic Acid SCHEMBL5562752 | 0.93 | CHEK1 (0.38) | DYRK1AGSK3BCHEK1 | |
| SCHEMBL1176658 | 0.89 | CHEK1 (0.40) | DYRK1AGSK3BCHEK1 | |
| SCHEMBL1176364 | 0.89 | CHEK1 (0.40) | DYRK1AGSK3BCHEK1 | |
| Formic Acid SCHEMBL5562314 | 0.86 | CHEK1 (0.38) | DYRK1AGSK3BCHEK1 | |
| Formic Acid SCHEMBL5561867 | 0.86 | DYRK1A (0.40) | DYRK1AGSK3BWNT1CHEK1CLK2 | |
| Formic Acid SCHEMBL5562437 | 0.85 | DYRK1A (0.46) | DYRK1AGSK3BWNT1CLK2CLK3 | |
| Formic Acid SCHEMBL5561468 | 0.85 | HAO1 (0.42) | DYRK1AGSK3BWNT1CLK2CLK3 | |
| Formic Acid SCHEMBL5563261 | 0.85 | GSK3B (0.40) | DYRK1AGSK3BWNT1CHEK1CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697378-B1 | INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, AND 1,2-BENZISOTHIAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARM CORP (US) | 2007-11-21 | — | — | EP | claimed |