Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 13/20 | 0.39 |
| ▸ | WNT1 | P04628 | 6/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK3 | P49761 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176793 | 0.96 | GSK3B (0.42) | GSK3BCDK2GSK3ADYRK1AWNT1 | |
| SCHEMBL1175940 | 0.96 | GSK3B (0.42) | GSK3BCDK2GSK3ADYRK1AWNT1 | |
| Formic Acid SCHEMBL5562073 | 0.93 | CDK2 (0.46) | GSK3BCDK2GSK3AFGFR4CHEK1 | |
| SCHEMBL1176462 | 0.89 | CDK2 (0.48) | GSK3BCDK2GSK3AFGFR4CHEK1 | |
| SCHEMBL1176466 | 0.89 | CDK2 (0.48) | GSK3BCDK2GSK3AFGFR4CHEK1 | |
| Formic Acid SCHEMBL5562045 | 0.87 | DYRK1A (0.38) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| Formic Acid SCHEMBL5562289 | 0.87 | DYRK1A (0.39) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| Formic Acid SCHEMBL5563457 | 0.86 | DYRK1A (0.52) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| Formic Acid SCHEMBL5562969 | 0.85 | DYRK1A (0.38) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| Formic Acid SCHEMBL5561867 | 0.85 | DYRK1A (0.40) | GSK3BCDK2GSK3ADYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697378-B1 | INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, AND 1,2-BENZISOTHIAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARM CORP (US) | 2007-11-21 | — | — | EP | claimed |