Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 16/20 | 0.40 |
| ▸ | GSK3B | P49841 | 6/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | WNT1 | P04628 | 7/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176212 | 0.93 | BRD4 (0.39) | BRD4MTORLRRK2CHRNA7KCNH2 | |
| SCHEMBL5044455 | 0.93 | BRD4 (0.39) | BRD4MTORLRRK2CHRNA7KCNH2 | |
| Formic Acid SCHEMBL5561750 | 0.89 | BRD4 (0.37) | BRD4MTORLRRK2CHRNA7KCNH2 | |
| SCHEMBL1176497 | 0.84 | CDK2 (0.42) | DYRK1AGSK3BWNT1 | |
| SCHEMBL5047046 | 0.84 | CDK2 (0.42) | DYRK1AGSK3BWNT1 | |
| SCHEMBL1176154 | 0.83 | DYRK1A (0.42) | DYRK1AGSK3BWNT1LRRK2 | |
| SCHEMBL5048309 | 0.83 | DYRK1A (0.42) | DYRK1AGSK3BWNT1LRRK2 | |
| SCHEMBL5042792 | 0.82 | DYRK1A (0.56) | DYRK1AGSK3BWNT1 | |
| SCHEMBL1176610 | 0.82 | DYRK1A (0.56) | DYRK1AGSK3BWNT1 | |
| SCHEMBL1175586 | 0.82 | DYRK1A (0.56) | DYRK1AGSK3BWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697378-B1 | INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, AND 1,2-BENZISOTHIAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARM CORP (US) | 2007-11-21 | — | — | EP | claimed |