Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2417979 | 0.90 | PPARA (0.39) | PPARAGABRA5GABRB2HSD17B10SLC22A12 | |
| SCHEMBL2415348 | 0.86 | HSD17B10 (0.49) | PPARAGABRA5GABRB2HSD17B10KDM4E | |
| SCHEMBL2409115 | 0.85 | PPARA (0.39) | PPARASLC22A12 | |
| SCHEMBL2409692 | 0.82 | PPARA (0.32) | PPARACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22334824 | 0.79 | ALDH1A1 (0.44) | PPARAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL2415156 | 0.76 | MAPT (0.42) | PPARAHSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL2409605 | 0.76 | MEN1 (0.57) | CYP1A2CYP2D6CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL2418139 | 0.76 | POLQ (0.41) | PPARANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL2411454 | 0.76 | PPARA (0.36) | PPARACYP2C9CYP2C19SLC22A12SMN1; SMN2 | |
| SCHEMBL5988608 | 0.75 | HSD17B10 (0.37) | CYP1A2CYP2D6CYP2C9CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1816128-A1 | CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2007-08-08 | — | — | EP | disclosed |