Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 19/20 | 0.55 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | WNT1 | P04628 | 8/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176384 | 0.96 | DYRK1A (0.58) | DYRK1AGSK3BWNT1 | |
| SCHEMBL5046313 | 0.96 | DYRK1A (0.58) | DYRK1AGSK3BWNT1 | |
| Formic Acid SCHEMBL5557042 | 0.92 | DYRK1A (0.53) | DYRK1AGSK3BWNT1 | |
| Formic Acid SCHEMBL5563457 | 0.91 | DYRK1A (0.52) | DYRK1AGSK3BWNT1 | |
| SCHEMBL5042846 | 0.88 | DYRK1A (0.56) | DYRK1AGSK3BWNT1 | |
| SCHEMBL1175586 | 0.88 | DYRK1A (0.56) | DYRK1AGSK3BWNT1 | |
| SCHEMBL1176610 | 0.87 | DYRK1A (0.56) | DYRK1AGSK3BWNT1 | |
| SCHEMBL5042792 | 0.87 | DYRK1A (0.56) | DYRK1AGSK3BWNT1 | |
| SCHEMBL5562209 | 0.85 | DYRK1A (0.51) | DYRK1AGSK3BWNT1 | |
| Formic Acid SCHEMBL5561851 | 0.85 | PRKAG1 (0.54) | DYRK1AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697378-B1 | INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, AND 1,2-BENZISOTHIAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARM CORP (US) | 2007-11-21 | — | — | EP | claimed |