Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 11/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1695486 | 0.85 | KMT2A (0.49) | KMT2ASIRT1TSHRNOTUMPOLB | |
| SCHEMBL11995109 | 0.76 | ABCG2 (0.42) | KMT2ASIRT1TSHRNOTUMPOLB | |
| SCHEMBL5559760 | 0.75 | TSHR (0.58) | KMT2ATSHRPOLBALDH1A1MAPT | |
| SCHEMBL6173541 | 0.74 | NOTUM (0.51) | KMT2ASIRT1TSHRNOTUMPOLB | |
| SCHEMBL31547779 | 0.74 | CYP2C9 (0.39) | KMT2ASIRT1TSHRSIRT2NOTUM | |
| Paraxazone SCHEMBL2108049 | 0.73 | KMT2A (0.67) | KMT2ATSHRPOLBALDH1A1MAPT | |
| SCHEMBL27672516 | 0.73 | HPGD (0.40) | KMT2ASIRT1TSHRNOTUM | |
| SCHEMBL9134742 | 0.73 | CYP2C9 (0.40) | KMT2ATSHRNOTUM | |
| SCHEMBL11558067 | 0.72 | NPC1 (0.40) | KMT2ASIRT1TSHRSIRT2ALDH1A1 | |
| SCHEMBL11557307 | 0.71 | NPC1 (0.39) | KMT2ASIRT1TSHRSIRT2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756071-A1 | BENZOXAZOLONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB, S.A. (BE) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005118561-A1 | BENZOXAZOLONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB, S.A. (BE) | 2005-12-15 | — | — | WO | disclosed |