Paraxazone

Paraxazone

SCHEMBL2108049

NC(=O)CN1C(=O)COc2ccccc21

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.67
MEN1 O00255 2/20 0.67
TSHR P16473 1/20 0.64
POLB P06746 2/20 0.62
LMNA P02545 1/20 0.62
CBX7 O95931 3/20 0.61
CDYL2 Q8N8U2 3/20 0.61
CDYL Q9Y232 3/20 0.61
CDY1; CDY1B Q9Y6F8 2/20 0.61
ALDH1A1 P00352 3/20 0.60
GAA P10253 2/20 0.60
HTT P42858 1/20 0.60
USP2 O75604 1/20 0.60
KDM4E B2RXH2 1/20 0.60
MAPT P10636 1/20 0.60
ALOX12 P18054 1/20 0.58
CYP2C9 P11712 1/20 0.58
CYP2C19 P33261 1/20 0.58
TP53 P04637 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4970176 0.86 KMT2A (0.68) KMT2AMEN1TSHRPOLBLMNA
SCHEMBL30808661 0.86 KMT2A (0.68) KMT2AMEN1TSHRPOLBLMNA
SCHEMBL4432608 0.85 KMT2A (0.67) KMT2AMEN1TSHRPOLBLMNA
SCHEMBL30808581 0.84 ALDH1A1 (0.66) KMT2AMEN1TSHRPOLBLMNA
SCHEMBL30336808 0.81 HTT (0.47) KMT2AMEN1TSHRPOLBLMNA
SCHEMBL29209149 0.81 HTT (0.47) KMT2AMEN1TSHRPOLBLMNA
SCHEMBL14046919 0.81 TSHR (0.63) KMT2AMEN1TSHRPOLBLMNA
SCHEMBL4968483 0.81 ALDH1A1 (0.66) KMT2AMEN1TSHRPOLBLMNA
SCHEMBL8225730 0.81 KMT2A (0.61) KMT2AMEN1TSHRPOLBLMNA
SCHEMBL11982070 0.80 TSHR (0.78) KMT2AMEN1TSHRPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-11383084-B2 Treatment of dermatological conditions via neuromodulation PALO ALTO INVESTORS (US) 2022-07-12 US disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-20210393674-A1 OZONOLYSIS FOR ACTIVATION OF COMPOUNDS AND DEGRADATION OF OZONE AIR CROSS, INC 2021-12-23 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
US-20180311499-A1 Treatment of Dermatological Conditions via Neuromodulation PALO ALTO INVESTORS 2018-11-01 US disclosed
CN-108348894-A Ozonolysis for compound activation and ozonolysis 空气交叉股份有限公司 2018-07-31 CN disclosed
CN-1093123-C Lactams and imides of aralkyl and arylalkylene heterocycles PFIZER (US) 2002-10-23 CN disclosed
US-20020102215-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-20020102217-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
CN-1329002-A Intermediate product for preparing aralkyl and aryl alkylene heterocyclic lactam and imide PFIZER (US) 2002-01-02 CN disclosed
US-6331289-B1 ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED NYCOMED IMAGING AS (NO) 2001-12-18 US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed
CN-1231661-A Lactams and imides of aralkyl and arylalkylene heterocycles PFIZER (US) 1999-10-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210393674-A1 OZONOLYSIS FOR ACTIVATION OF COMPOUNDS AND DEGRADATION OF OZONE DUOX1, DUOX2, AOX1 KMT2A 3488/4885MEN1 3061/4885TSHR 3902/4885
US-20020102215-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 KMT2A 4411/4885MEN1 671/4885TSHR 1871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.