Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 1.00 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.78 |
| ▸ | EGFR | P00533 | 10/20 | 0.76 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.68 |
| ▸ | GAK | O14976 | 2/20 | 0.68 |
| ▸ | KDR | P35968 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.68 |
| ▸ | ABL1 | P00519 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CDK1 | P06493 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | SRC | P12931 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27998800 | 0.86 | ABCG2 (0.76) | FBP1ABCG2EGFRERBB2GAK | |
| SCHEMBL6668347 | 0.86 | FBP1 (0.76) | FBP1ABCG2EGFRERBB2GAK | |
| SCHEMBL12069892 | 0.85 | FBP1 (0.74) | FBP1ABCG2EGFRKDREPHB2 | |
| SCHEMBL5570060 | 0.85 | FBP1 (0.74) | FBP1ABCG2EGFRERBB2KDR | |
| Hydrochloric Acid SCHEMBL8809754 | 0.81 | FBP1 (0.68) | FBP1ABCG2EGFRKDRSRC | |
| SCHEMBL29444884 | 0.81 | EGFR (1.00) | FBP1ABCG2EGFRERBB2GAK | |
| SCHEMBL9423 | 0.81 | EGFR (1.00) | FBP1ABCG2EGFRERBB2GAK | |
| SCHEMBL30363011 | 0.81 | EGFR (1.00) | FBP1ABCG2EGFRERBB2GAK | |
| SCHEMBL5568019 | 0.80 | ABCG2 (0.80) | FBP1ABCG2EGFRERBB2ABCB1 | |
| Hydrochloric Acid SCHEMBL30362813 | 0.80 | EGFR (1.00) | FBP1ABCG2EGFRERBB2GAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123537-A1 | Quinazoline derivatives for the treatment of herpesviral infections | GPC BIOTECH AG (DE) | 2007-05-31 | — | — | US | claimed |
| US-20070123537-A1 | Quinazoline derivatives for the treatment of herpesviral infections | GPC BIOTECH AG (DE) | 2007-05-31 | — | — | US | disclosed |
| EP-1673346-A1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF HERPESVIRAL INFECTIONS | GPC Biotech AG (DE) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005040125-A1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF HERPESVIRAL INFECTIONS | GPC BIOTECH AG (DE) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123537-A1 | Quinazoline derivatives for the treatment of herpesviral infections | IRF3, PML, TPMT | FBP1 1906/4885ABCG2 311/4885EGFR 1445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.