Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzaldehyde SCHEMBL28051518 | 0.81 | CYP2C19 (0.58) | CYP2C19KMT2ANPSR1MEN1HTT | |
| SCHEMBL8925834 | 0.78 | CYP2C19 (1.00) | CYP2C19KMT2ANPSR1MEN1HTT | |
| SCHEMBL4237838 | 0.78 | CYP2C19 (1.00) | CYP2C19KMT2ANPSR1MEN1HTT | |
| SCHEMBL28551481 | 0.78 | CYP2C19 (1.00) | CYP2C19KMT2ANPSR1MEN1HTT | |
| SCHEMBL16710294 | 0.78 | CYP2C19 (1.00) | CYP2C19KMT2ANPSR1MEN1HTT | |
| SCHEMBL30311459 | 0.75 | NPSR1 (0.54) | CYP2C19KMT2ANPSR1MEN1HTT | |
| SCHEMBL10409062 | 0.75 | CYP2C19 (0.53) | CYP2C19KMT2ANPSR1MEN1HTT | |
| SCHEMBL10409063 | 0.75 | CYP2C19 (0.53) | CYP2C19KMT2ANPSR1MEN1HTT | |
| SCHEMBL28459427 | 0.74 | CYP2C19 (0.76) | CYP2C19KMT2ANPSR1MEN1HTT | |
| SCHEMBL7543920 | 0.74 | CYP2C19 (0.62) | CYP2C19KMT2ANPSR1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1769286-A2 | OXIME DERIVATIVES AND THE USE THEROF AS LATENT ACIDS | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006008250-A2 | OXIME DERIVATIVES AND THE USE THEROF AS LATENT ACIDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-01-26 | — | — | WO | disclosed |