Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088421 | 0.80 | KDM1A (0.36) | KDM1AKMT2AMEN1JAK2LMNA | |
| SCHEMBL8830381 | 0.78 | KDM1A (0.35) | KDM1AKMT2AMEN1JAK2LMNA | |
| SCHEMBL30052413 | 0.76 | TRPA1 (0.35) | KDM1ALMNAMAPTHTT | |
| SCHEMBL4742842 | 0.74 | MAPT (0.35) | KDM1AKMT2AMEN1JAK2LMNA | |
| SCHEMBL9555439 | 0.74 | MAPT (0.35) | KDM1AKMT2AMEN1JAK2LMNA | |
| SCHEMBL1966472 | 0.74 | GLA (0.40) | KMT2AMEN1JAK2LMNAMAPT | |
| SCHEMBL8058925 | 0.74 | KDM1A (0.32) | KDM1AKMT2AMEN1LMNAMAPT | |
| SCHEMBL29962540 | 0.72 | KDM1A (0.42) | KDM1AKMT2AMEN1JAK2LMNA | |
| SCHEMBL28413151 | 0.72 | KDM1A (0.42) | KDM1AKMT2AMEN1JAK2LMNA | |
| SCHEMBL30874319 | 0.72 | KDM1A (0.38) | KDM1AKMT2AMEN1JAK2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748988-A1 | A PROCESS FOR THE PREPARATION OF IMINOSTILBENE DERIVATIVES | Milanese, Alberto (IT) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005118550-A1 | A PROCESS FOR THE PREPARATION OF IMINOSTILBENE DERIVATIVES | MILANESE ALBERTO (IT) | 2005-12-15 | — | — | WO | disclosed |
| US-5808058-A | Process for the preparation of 10-OXO-10, 11-dihydro-5H-dibenz (b,f) azepin-5-carboxamide | TRIFARMA S.R.L. (IT) | 1998-09-15 | — | — | US | disclosed |