Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 12/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104932 | 0.80 | APP (0.58) | APPMAOBCYP1A2CA9KDM4E | |
| Acetic Acid SCHEMBL233001 | 0.75 | APP (0.59) | APPMAOACYP1A2KDM4E | |
| SCHEMBL6840173 | 0.73 | ELANE (0.44) | MAOBMAOAIDO1CYP1A2CA9 | |
| SCHEMBL28856792 | 0.72 | MAOB (0.41) | MAOBMAOAIDO1CYP1A2CA9 | |
| SCHEMBL14680386 | 0.72 | MAOA (0.85) | MAOBMAOAIDO1CYP1A2CA9 | |
| SCHEMBL8067 | 0.70 | APP (0.65) | APPCYP1A2KDM4E | |
| Pivalate SCHEMBL6813805 | 0.69 | APP (0.56) | APPCYP1A2KDM4E | |
| SCHEMBL6813575 | 0.69 | APP (0.56) | APPMAOACYP1A2KDM4E | |
| Water SCHEMBL1094033 | 0.69 | APP (0.63) | APPCYP1A2KDM4E | |
| SCHEMBL1096453 | 0.69 | APP (0.63) | APPCYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163815-B2 | Methods and compositions for NAD(P)(H) oxidases | GEORGIA TECH RESEARCH CORPORATION (US) | 2007-01-16 | — | — | US | disclosed |
| US-20050196788-A1 | Methods and compositions for NAD(P)(H) oxidases | GEORGIA TECH RESEARCH CORPORATION (US) | 2005-09-08 | — | — | US | disclosed |
| WO-2004011670-A2 | METHODS AND COMPOSITIONS FOR NAD(P)(H) OXIDASES | GEORGIA TECH RESEARCH CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |