Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5562053 | 0.92 | CNR1 (0.98) | CNR1CNR2 | |
| SCHEMBL5567271 | 0.88 | CNR1 (0.98) | CNR1CNR2 | |
| SCHEMBL5646976 | 0.82 | CNR1 (0.90) | CNR1CNR2 | |
| SCHEMBL5562587 | 0.82 | CNR1 (0.98) | CNR1CNR2 | |
| SCHEMBL5561839 | 0.82 | CNR1 (0.98) | CNR1 | |
| SCHEMBL5567261 | 0.82 | CNR1 (0.80) | CNR1CNR2 | |
| SCHEMBL5567975 | 0.80 | CNR1 (0.98) | CNR1 | |
| SCHEMBL5563280 | 0.80 | CNR1 (0.73) | CNR1CNR2 | |
| SCHEMBL5561937 | 0.79 | CNR1 (0.72) | CNR1 | |
| Fumaric Acid SCHEMBL5562031 | 0.78 | CNR1 (1.00) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304064-B2 | 1-[(indol-3-yl)carbonyl]piperazine derivatives | N.V. ORGANON (NL) | 2007-12-04 | — | — | US | disclosed |
| EP-1549637-B1 | 1- (INDOL-3-YL)CARBONYL PIPERAZINE DERIVATIVES | ORGANON NV (NL) | 2007-05-02 | — | — | EP | disclosed |
| US-20050250760-A1 | 1-[(Indol-3-yl)carbonyl]piperazine derivatives | MERCK SHARP & DOHME B.V. (NL) | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250760-A1 | 1-[(Indol-3-yl)carbonyl]piperazine derivatives | IDO1, OPRL1, OPRK1 | CNR1 13/4885CNR2 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.