Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 10/20 | 0.49 |
| ▸ | PON1 | P27169 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL17926156 | 1.00 | MEN1 (0.55) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL17926158 | 0.98 | MEN1 (0.54) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL329124 | 0.98 | MEN1 (0.53) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL19857300 | 0.96 | MEN1 (0.51) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Iodide SCHEMBL17273606 | 0.96 | MEN1 (0.51) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Hydrochloric Acid SCHEMBL558001 | 0.96 | MEN1 (0.51) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL28490546 | 0.96 | MEN1 (0.51) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL16674121 | 0.96 | MEN1 (0.51) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL16673900 | 0.94 | MEN1 (0.50) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL16674099 | 0.94 | MEN1 (0.54) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112067674-A | Molecular imprinting electrochemical sensor and method for detecting folic acid content by using same | 常州市新鸿医药化工技术有限公司 | 2020-12-11 | — | — | CN | claimed |
| CN-107342434-B | Rechargeable aluminium battery using ordered mesopore carbon as positive electrode and preparation method thereof | 济南大学 | 2019-07-05 | — | — | CN | claimed |
| CN-107342434-A | A kind of rechargeable aluminium battery using ordered mesopore carbon as positive electrode and preparation method thereof | 济南大学 | 2017-11-10 | — | — | CN | claimed |
| US-8420732-B2 | Polybenzimidazole solution in an ionic liquid | PBI PERFORMANCE PRODUCTS, INC. (US) | 2013-04-16 | — | — | US | claimed |
| WO-2012087442-A1 | POLYBENZIMIDAZOLE SOLUTION IN AN IONIC LIQUID | PBI PERFORMANCE PRODUCTS, INC. (US) | 2012-06-28 | — | — | WO | claimed |
| US-20120142830-A1 | POLYBENZIMIDAZOLE SOLUTION IN AN IONIC LIQUID | DAWKINS BOBBY G (US) | 2012-06-07 | — | — | US | claimed |
| US-20110152413-A1 | POLYBENZIMIDAZOLE SOLUTION IN AN IONIC LIQUID | PBI PERFORMANCE PRODUCTS, INC. | 2011-06-23 | — | — | US | claimed |
| CN-109803976-B | Palladium (II) complexes containing N-heterocyclic carbene ligands, synthesis, and use in cancer therapy | 香港大学 | 2022-02-11 | — | — | CN | disclosed |
| CN-213302075-U | Molecular imprinting electrochemical sensor and device for detecting folic acid content | 常州市新鸿医药化工技术有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-112067674-A | Molecular imprinting electrochemical sensor and method for detecting folic acid content by using same | 常州市新鸿医药化工技术有限公司 | 2020-12-11 | — | — | CN | disclosed |
| US-20190291046-A1 | OXYGEN SEPARATION MEMBRANE | SHARP KABUSHIKI KAISHA (JP) | 2019-09-26 | — | — | US | disclosed |
| CN-107342434-B | Rechargeable aluminium battery using ordered mesopore carbon as positive electrode and preparation method thereof | 济南大学 | 2019-07-05 | — | — | CN | disclosed |
| CN-107342434-B | Rechargeable aluminium battery using ordered mesopore carbon as positive electrode and preparation method thereof | 济南大学 | 2019-07-05 | — | — | CN | disclosed |
| US-20120142830-A1 | POLYBENZIMIDAZOLE SOLUTION IN AN IONIC LIQUID | DAWKINS BOBBY G (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120052324-A1 | Electric Al-Zr-Mn Alloy-Plating Bath Using Room Temperature Molten Salt Bath, Plating Method Using the Same and Al-Zr-Mn Alloy-Plated Film | HONDA MOTOR CO., LTD. (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20120031766-A1 | Electric Al or Al Alloy Plating Bath Using Room Temperature Molten Salt Bath and Plating Method Using the Same | HONDA MOTOR CO., LTD. (JP) | 2012-02-09 | — | — | US | disclosed |
| US-20110152413-A1 | POLYBENZIMIDAZOLE SOLUTION IN AN IONIC LIQUID | PBI PERFORMANCE PRODUCTS, INC. | 2011-06-23 | — | — | US | disclosed |
| US-20100285322-A1 | Electric Al-Zr Alloy Plating Bath Using Room Temperature Molten Salt Bath and Plating Method Using the Same | DIPSOL CHEMICALS CO., LTD. (JP) | 2010-11-11 | — | — | US | disclosed |
| EP-2130949-A1 | ELECTRIC Al-Zr ALLOY PLATING BATH USING ROOM TEMPERATURE MOLTEN SALT BATH AND PLATING METHOD USING THE SAME | Dipsol Chemicals Co., Ltd. (JP) | 2009-12-09 | — | — | EP | disclosed |
| CN-1706878-A | Metal-less N-heterocyclic carbone catalyst and its prepn process | UNIV ZHEJIANG (CN) | 2005-12-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190291046-A1 | OXYGEN SEPARATION MEMBRANE | NCLN, OXA1L, MB | MEN1 1040/4885HSP90AA1 4421/4885KMT2A 2088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.