Sugi Predict

Sugi Predict / Targets / NCLN

NCLN

BOS complex subunit NCLN · Q969V3 · NCLN on Sugi Atlas →

0 patent compounds predicted against NCLN, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to NCLN by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Safety Study of a Gene Transfer Vector (Rh.10) for Children With Late Infantile Neuronal Ceroid Lipofuscinosis (LINCL) PHASE1COMPLETED
Investigations of Juvenile Neuronal Ceroid Lipofuscinosis nanRECRUITING
Natural History of Neuronal Ceroid Lipofuscinosis, Batten's CLN6 Diseae nanACTIVE_NOT_RECRUITING
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients nanRECRUITING
Investigations Into ISCU Myopathy or Iron Sulfur Scaffold U Protein Myopathy nanCOMPLETED
Identification of New FTLD Genes nanUNKNOWN
Natural History and Longitudinal Clinical Assessments in NCL / Batten Disease, the International DEM-CHILD Database nanRECRUITING
Mitochondrial Membrane Protein Neurodegeneration (MPAN) nanCOMPLETED
Testing of NBIA Genes: Analysis of Genetic Heterogeneity and Validation of Mitochondrial Markers for Assessing Causality of Sequence Variants. nanCOMPLETED
External Nitric Oxide Measurement Through SNO Degradation nanENROLLING_BY_INVITATION
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
NCF Gene & TNFSF4 in SLE Patients nanUNKNOWN
Clinical and Biochemical Features for the Identification of Dominant Calpainopathies nanUNKNOWN
Genetic Diagnosis in Inborn Errors of Metabolism nanENROLLING_BY_INVITATION
Phenotype/Genotype Correlations in Neuromuscular Disorders nanCOMPLETED
Somatosensory Phenotype of Patients Suffering From Unspecific Neck and Arm Pain nanCOMPLETED
Molecular and Genetic Studies of Congenital Myopathies nanRECRUITING
Role of the Nuclear Pore Component RANBP2 in Inflammatory Responses to Viral Infections nanCOMPLETED
Italian NCL Registry: a Registry for NCL as an Integration Tool for Future Therapeutic Strategies nanRECRUITING
Genetics of Familial and Sporadic ALS nanCOMPLETED
Genetic Analysis of Hereditary Non-Syndromic Oral Clefts nanCOMPLETED
Amyotrophic Lateral Sclerosis (ALS) Families Project nanRECRUITING
Genetic Newborn Screening for Cystinosis and Primary Hyperoxaluria nanRECRUITING
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC) nanRECRUITING
Neuronal Ceroid Lipofuscinosis and Associated Sleep Abnormalities nanCOMPLETED
Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults nanCOMPLETED
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer nanUNKNOWN
Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease nanCOMPLETED
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a NCLN binder may also engage these)

ProteinNameSimilarity
Q8VCM8 — 1.000 Q8VCM8 →
Q5XIA1 — 1.000 Q5XIA1 →
Q6NZ07 — 1.000 Q6NZ07 →
A0A8I3NGV2 — 1.000 A0A8I3NGV2 →
Q5ZJH2 — 1.000 Q5ZJH2 →
NCSTN Nicastrin 0.986 landscape →
P57716 — 0.983 P57716 →
Q8CGU6 — 0.975 Q8CGU6 →
Q5RDH6 — 0.970 Q5RDH6 →
Q28DV7 — 0.970 Q28DV7 →
GPAA1 GPI-anchor transamidase component GPAA1 0.969 landscape →
TFRC Transferrin receptor protein 1 0.969 landscape →
Q9BRR6 — 0.969 Q9BRR6 →
Q9GLD3 — 0.969 Q9GLD3 →
PIGT GPI-anchor transamidase component PIGT 0.969 landscape →
EMC1 ER membrane protein complex subunit 1 0.968 landscape →
Q9ESJ4 — 0.968 Q9ESJ4 →
Q8BXQ2 — 0.968 Q8BXQ2 →
P47823 — 0.968 P47823 →
NAT10 RNA cytidine acetyltransferase 0.967 landscape →
Q7ZYP6 — 0.967 Q7ZYP6 →
Q9NZQ3 — 0.967 Q9NZQ3 →
CPSF1 Cleavage and polyadenylation specificity factor subunit 1 0.966 landscape →
Q3UR70 — 0.966 Q3UR70 →
Q9WTK3 — 0.966 Q9WTK3 →
Q2V905 — 0.966 Q2V905 →
Q9DBG6 — 0.966 Q9DBG6 →
F1PCT7 — 0.966 F1PCT7 →
Q8R553 — 0.966 Q8R553 →
Q07891 — 0.966 Q07891 →