Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.51 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 11/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5568371 | 0.99 | F10 (0.51) | F10ARNPC1ALDH1A1MAPT | |
| SCHEMBL6457953 | 0.86 | F10 (0.68) | F10ARNPC1ALDH1A1MAPT | |
| SCHEMBL6455327 | 0.85 | F10 (0.67) | F10ARNPC1ALDH1A1MAPT | |
| SCHEMBL5567351 | 0.83 | F10 (0.50) | F10ARNPC1RAB9ANPY2R | |
| SCHEMBL5561433 | 0.82 | F10 (0.48) | F10ARNPC1ALDH1A1MAPT | |
| SCHEMBL5512209 | 0.81 | F10 (0.66) | F10ARNPC1ALDH1A1MAPT | |
| SCHEMBL5504066 | 0.76 | F10 (0.46) | F10ARNPC1MAPTRAB9A | |
| SCHEMBL5562224 | 0.74 | F10 (0.40) | F10ARNPC1RAB9AKDM4E | |
| SCHEMBL5504077 | 0.74 | F10 (0.42) | F10ARNPC1MAPTRAB9A | |
| SCHEMBL5503712 | 0.74 | F10 (0.38) | F10ARNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748997-A1 | SUBSTITUTED THIOPHENE-2-CARBOXYLIC ACID AMIDES, THE PRODUCTION THEREOF AND THE USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005111013-A1 | SUBSTITUTED THIOPHENE-2-CARBOXYLIC ACID AMIDES, THE PRODUCTION THEREOF AND THE USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |