Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.68 |
| ▸ | AR | P10275 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.41 |
| ▸ | RELA | Q04206 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6455327 | 0.99 | F10 (0.67) | F10ARSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5567299 | 0.86 | F10 (0.51) | F10ARSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6462937 | 0.85 | F10 (0.78) | F10ARSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5568371 | 0.85 | F10 (0.51) | F10ARSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6454976 | 0.84 | F10 (0.65) | F10ARSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6455260 | 0.83 | F10 (0.68) | F10ARSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6462057 | 0.82 | F10 (0.63) | F10ARSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6455289 | 0.82 | F10 (0.67) | F10ARSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6455350 | 0.81 | F10 (0.64) | F10ARSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6455305 | 0.81 | F10 (0.64) | F10ARSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256107-A1 | New substituted thiophene carboxamides, process for their preparation and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256107-A1 | New substituted thiophene carboxamides, process for their preparation and their use as medicaments | OTC, TPMT, ABCG2 | F10 1901/4885AR 3491/4885SMN1; SMN2 3283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.