Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5563634 | 0.83 | PDE5A (0.41) | PDE5AKMT2AGAAMAPT | |
| SCHEMBL3256076 | 0.83 | PDE5A (0.41) | PDE5AKMT2AGAAMAPT | |
| SCHEMBL10307911 | 0.82 | EP300 (0.41) | KMT2AGAAMAPT | |
| SCHEMBL19317176 | 0.82 | KMT2A (0.40) | KMT2AGAAMAPT | |
| SCHEMBL30132930 | 0.82 | EP300 (0.41) | KMT2AGAAMAPT | |
| SCHEMBL5917429 | 0.81 | PDE5A (0.44) | PDE5AGAAMAPT | |
| SCHEMBL8208975 | 0.80 | GAA (0.56) | GAAMAPT | |
| SCHEMBL5567732 | 0.78 | GAA (0.44) | KMT2AGAAMAPT | |
| SCHEMBL7043179 | 0.78 | MAPT (0.41) | KMT2AGAAMAPT | |
| SCHEMBL926189 | 0.77 | GAA (0.40) | KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042288-B1 | TRIPEPTIDYL PEPTIDASE INHIBITORS | INST NAT SANTE RECH MED (FR) | 2007-11-07 | — | — | EP | disclosed |
| US-6335360-B1 | INDOLINE-2-CARBOXYLIC AMIDE DERIVATIVES; OBESITY, EATING AND PSYCHOLOGICAL DISORDERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-01-01 | — | — | US | disclosed |