Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906592 | 0.85 | MGAM (0.44) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL2912543 | 0.85 | MGAM (0.44) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL2912840 | 0.85 | MGAM (0.44) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL29309522 | 0.83 | MGAM (0.38) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL15344 | 0.83 | GAA (0.58) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL5563470 | 0.81 | MGAM (0.41) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL31260805 | 0.81 | GAA (0.56) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL14297014 | 0.80 | GAA (0.50) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL17635506 | 0.77 | GAA (0.47) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL29133365 | 0.76 | GAA (0.45) | MGAMGAASIMGAM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169890-B2 | Process for the production of ramoplanin-like amide derivatives | VICURON PHARMACEUTICALS INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-20050106691-A1 | Process for the production of ramoplanin-like amide derivatives | VICURON PHARMACEUTICALS INC. (US) | 2005-05-19 | — | — | US | disclosed |
| EP-1483286-A1 | A PROCESS FOR THE PRODUCTION OF RAMOPLANIN-LIKE AMIDE DERIVATIVES | Vicuron Pharmaceuticals, Inc. (US) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003076460-A1 | A PROCESS FOR THE PRODUCTION OF RAMOPLANIN-LIKE AMIDE DERIVATIVES | VICURON PHARMACEUTICALS INC. (US) | 2003-09-18 | — | — | WO | disclosed |