Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.65 |
| ▸ | FAP | Q12884 | 1/20 | 0.65 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.65 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.65 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.65 |
| ▸ | ACE | P12821 | 6/20 | 0.56 |
| ▸ | REN | P00797 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PEPD | P12955 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30314724 | 0.91 | DPP4 (0.63) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL22872683 | 0.89 | DPP4 (0.65) | DPP4FAPDPP8DPP9DPP7 | |
| Bromide SCHEMBL7279605 | 0.87 | DPP4 (0.64) | DPP4FAPDPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL7409750 | 0.87 | DPP4 (0.64) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL29610030 | 0.87 | DPP4 (0.59) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL2113947 | 0.87 | DPP4 (0.59) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL2113944 | 0.87 | DPP4 (0.59) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL7411986 | 0.86 | DPP4 (0.62) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL2113410 | 0.86 | DPP7 (0.65) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL2113409 | 0.86 | DPP7 (0.65) | DPP4FAPDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841257-B2 | Inhibitors of STAT3 and uses thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-09-23 | — | — | US | disclosed |
| US-20120035114-A1 | INHIBITORS OF STAT3 AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-02-09 | — | — | US | disclosed |
| WO-2010118309-A2 | INHIBITORS OF STAT3 AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035114-A1 | INHIBITORS OF STAT3 AND USES THEREOF | STAT3, JAK2, STAT6 | DPP4 1512/4885FAP 2182/4885DPP8 1479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.